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Pharmaceutical Loratadine

Pharmaceutical Loratadine

13500 INR/Kilograms

Product Details:

  • Product Type Other Types
  • Form Other Form
  • Recommended For Doctor
  • Dosage As Per Doctor
  • Dosage Guidelines As Per Doctor Guideline
  • Storage Instructions Dry Place
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Pharmaceutical Loratadine Price And Quantity

  • 50 Kilograms
  • 13500 INR/Kilograms

Pharmaceutical Loratadine Product Specifications

  • Other Form
  • As Per Doctor Guideline
  • Doctor
  • Dry Place
  • As Per Doctor
  • Other Types

Pharmaceutical Loratadine Trade Information

  • bhavnagar
  • Cash Against Delivery (CAD) Cash Advance (CA) Cash in Advance (CID)
  • 50 Kilograms Per Day
  • 7 Days
  • Asia Australia Central America North America
  • All India

Product Description

We are instrumental in manufacturing, supplying and exporting pure quality Loratadine. This drug is well-formulated using high quality chemical components & elements under the proper guidance of our experienced and diligent experts so that the final output meets with the clients' demands. Our offered drug is useful for cold, cough and to treat allergies. Before the final dispatch, this drug is duly checked on various parameters to ensure accurate composition. Loratadine has a molecular formula C22H23ClN2O2 and molar mass 382.88 g/mol.



Loratadine is a widely used antihistamine medication Heres a detailed overview of its pharmaceutical profile


Description

Generic Name Loratadine

Brand Names Commonly sold under the brand names Claritin Alavert and others

Drug Class Antihistamine secondgeneration

Chemical Formula C22H23ClN2O2

Molecular Weight 38288 gmol

Appearance Available in various forms including tablets orally disintegrating tablets and syrup

Mechanism of Action

Loratadine is a selective antagonist of peripheral histamine H1 receptors By blocking these receptors it prevents the effects of histamine which is responsible for causing allergic symptoms such as itching sneezing and runny nose


Indications

Allergic Rhinitis Relief of symptoms associated with seasonal allergic rhinitis hay fever and perennial allergic rhinitis including sneezing runny or itchy nose and itchy or watery eyes

Chronic Urticaria Treatment of chronic idiopathic urticaria hives which includes relief from itching and the appearance of hives

Dosage

Adults and Children Over 12 Years Typically 10 mg once daily

Children Aged 6 to 11 Years Usually 5 mg once daily

Children Aged 2 to 5 Years Often administered as 25 mg once daily in syrup form although dosage may vary based on specific product formulations

Pharmacokinetics

Absorption Loratadine is wellabsorbed from the gastrointestinal tract with peak plasma concentrations occurring approximately 12 hours after oral administration

Distribution It is distributed throughout the body including the central nervous system though it tends to cross the bloodbrain barrier to a lesser extent compared to firstgeneration antihistamines

Metabolism Metabolized in the liver to its active metabolite desloratadine

Excretion Primarily eliminated through urine and feces with a halflife of approximately 814 hours

Side Effects

Common side effects may include


Headache

Dry mouth

Fatigue

Drowsiness less common compared to firstgeneration antihistamines

Gastrointestinal symptoms such as nausea

Serious side effects are rare but may include severe allergic reactions If any severe side effects occur medical attention should be sought


Precautions

Pregnancy Classified as Category B meaning there is no evidence of risk in humans based on animal studies however it should be used during pregnancy only if clearly needed and prescribed by a healthcare provider

Lactation Loratadine is excreted in breast milk so it should be used with caution during breastfeeding

Hepatic Impairment Dosage adjustments may be necessary for individuals with severe liver impairment as loratadine is metabolized by the liver

Interactions

Loratadine generally has fewer drug interactions compared to older antihistamines However it is still advisable to consult a healthcare provider if you are taking other medications particularly those affecting liver enzymes or those with sedative effects


Summary

Loratadine is an effective nonsedating antihistamine used for the relief of allergy symptoms It is welltolerated by most people and provides longlasting relief without the sedative effects common to firstgeneration antihistamines As with all medications it should be used according to a healthcare providers recommendations to ensure its safety and effectiveness







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